ASTIS
ASTIS
High Dose Immunoablation & Hematopoietic Stem Cell Transplantation vs Monthly Intravenous Pulse Therapy Cyclophosphomide (CPP) in Severe Systemic Sclerosis. A scleroderma therapeutic trial comparing the safety and efficacy of 2 different cyclophosphamide (CPP)-based therapeutic strategies: pulse therapy with CPP and the “gold standard” therapy vs autologous stem cell transplantation after obliterating the native bone marrow with megadoses of CPP.Conclusion The strategy may improve scleroderma management.