B cell

n. Any of a class of lymphocytes that, when activated by a specific antigen and usually also by helper T cells, proliferate and differentiate into antibody-secreting plasma cells or memory cells. In mammals, B cells mature in the bone marrow. Also called B lymphocyte.

[b(ursa-dependent) cell, after the bursa of Fabricius, a gland in birds where the cells mature and the first such tissue found in vertebrates.]

B cell

n. 1. Also called B lymphocyte. a type of white blood cell that circulates in the blood and lymph and produces antibody upon encountering any antigen that has a molecular arrangement complementary to the antibody. 2. beta cell. [1970–75]

B cell

Any of the lymphocytes that develop into plasma cells in the presence of a specific antigen, such as a bacterium or virus. The plasma cells then produce antibodies that attack or neutralize the antigen. B cells mature in the bone marrow before being released into the blood. See Note at antibody.

Thesaurus

Noun

B cell - a lymphocyte derived from bone marrow that provides humoral immunity; it recognizes free antigen molecules in solution and matures into plasma cells that secrete immunoglobulin (antibodies) that inactivate the antigensB lymphocytelymph cell, lymphocyte - an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection

B cell

1. β cell of pancreas or of anterior lobe of hypophysis; 2. Synonym(s): B lymphocyte

B cell

n. Any of the lymphocytes that when stimulated by a particular antigen differentiate into plasma cells and that in mammals mature in the bone marrow. Also called B lymphocyte.

B cell

One of the two major classes of lymphocytes, which comprises 30% of circulating lymphocytes and is concentrated in the follicular zones of lymphoid tissue (in contrast T cells, which are located in the deep cortex). B cells are responsible for antibody production, a transformation evoked by interaction with the appropriate CD4 T-helper cells. Igs are responsible for specific defence against viruses and bacteria, immune surveillance (cytolysis of potentially malignant “self” cells, mediation of antibody-dependent cell cytotoxicity), allergic reactions, formation of antigen-antibody complexes and production of cytokines; surface and cytoplasmic antigens indicate the degree of B-cell maturation and function. Cytoplasmic IgM is present in pre-B cells and surface Ig in mature B lymphoctytes and plasma cells; complement receptors are seen in mature cells. B cell markers include CD9, CD10, CD19, CD20, CD24, Fc receptor, B1, BA-1 and B4 Ia.

B cell

B lymphocyte Hematology One of the 2 major classes of lymphocytes, which comprises 30% of circulating lymphocytes and is concentrated in the follicular zones of lymphoid tissue–in contrast T cells is located in the deep cortex; B cells are responsible for antibody production, a transformation evoked by interaction with the appropriate CD4 T-helper cells; Igs are responsible for specific defense against viruses and bacteria, immune surveillance–cytolysis of potentially malignant 'self' cells, mediation of antibody-dependent cell cytotoxicity, allergic reactions, formation of antigen-antibody complexes, and production of cytokines; surface and cytoplasmic antigens indicate the degree of B cell maturation and function; cytoplasmic IgM is present in pre-B cells and surface Ig in mature B lymphoctytes and plasma cells; complement receptors are seen in mature cells; B cell 'markers' include CD9, CD10, CD19, CD20, CD24, Fc receptor, B1, BA-1, B4 Ia. See Pan B cell markers, Cf T cells.

B cell (B lymphocyte)

A type of white blood cell derived from bone marrow. B cells are sometimes called B lymphocytes. They secrete antibody and have a number of other complex functions within the human immune system.Mentioned in: AIDS Tests, Severe Combined Immunodeficiency, Waldenström's Macroglobulinemia, X-Linked Agammaglobulinemia

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Synonyms for B cell

noun a lymphocyte derived from bone marrow that provides humoral immunity

Synonyms

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