X-linked hypophosphatemic rickets

X-linked hypophosphatemic rickets

A condition characterized by impaired proximal renal tubule resorption of phosphate, coupled with a relative ↓ of 1,25-dihydroxyvitamin D production Clinical Growth failure, bowing of legs, hypophosphatemia, radiologic changes of rickets Management Calcitriol, phosphate Complications Kidney stone formation reflects phosphate levels