xanthogranulomatous pyelonephritis


xan·tho·gran·u·lo·ma·tous py·e·lo·ne·phri·tis

a form of pyelonephritis that results in a chronic inflammatory condition; the kidney enlarges and becomes less functional or nonfunctional; characterized histologically by the presence of lipid-laden, foamy macrophages and multiple granulomas. Can mimic neoplasms and renal tuberculosis and is a global process that affects the whole kidney.

xanthogranulomatous pyelonephritis

Nephrology A malakoplakia-like kidney lesion that lacks Michaelis-Gutmann bodies, arising in an E coli or Proteus spp infection Complications Hydronephrosis, nephrolithiasis

xanthogranulomatous pyelonephritis

Abbreviation: XGP
A relatively rare form of chronic destructive kidney infection in which a kidney, usually one obstructed by stones, becomes enlarged, necrotic, and functionless. In most cases the diseased kidney is surgically removed. See also: pyelonephritis