atypical fibroxanthoma


a·typ·i·cal fi·bro·xan·tho·ma

a solitary, often ulcerated, small, cutaneous, usually benign tumor composed of foamy histiocytes, spindle cells, and bizarre giant cells; usually found on the exposed skin of older people; microscopically, atypical fibroxanthoma closely resembles malignant fibrous histiocytoma, but originates in the dermis.

atypical fibroxanthoma

A cutaneous tumour seen in the head and neck of older individuals, which is linked to sun exposure and radiation therapy. It is characterised by a proliferation of spindle cells, many of which have bizarre and hyperchromatic nuclei, increased mitoses and atypical mitotic figures.