| 释义 |
Wolff-Chaikoff effect
Wolff-Chai·koff block (vulf chī'kof), obstruction of the organic binding of iodine and its incorporation into hormone, caused by large doses of iodine; usually transient, but in large doses in susceptible people, the effect can be prolonged and cause iodine myxedema. Synonym(s): Wolff-Chaikoff effect [Louis Wolff; Israel Chaikoff] Wolff-Chaikoff effect Endocrinology An acute adaptive response to high doses of iodine–↑ intracellular iodide blocks the organic-binding and coupling reactions in the thyroid, functionally turning off the thyroid; the WCE used to prepare the thyroid for surgery. See Hyperthyroidism. Wolff, Louis, U.S. cardiologist, 1898-1972. Wolff-Chaikoff block - blocking of the organic binding of iodine and its incorporation into hormone caused by large doses of iodine. Synonym(s): Wolff-Chaikoff effectWolff-Chaikoff effect - Synonym(s): Wolff-Chaikoff blockWolff-Parkinson-White syndrome - an electrocardiographic pattern sometimes associated with paroxysmal tachycardia. Synonym(s): preexcitation syndrome |