WHO staging system

WHO staging system

AIDS A simplified AIDS staging system proposed by the WHO Global Programme on AIDS that is flexible enough to be used in different regions, based on 4 groups of clinical conditions that have prognostic significance and therefore constitute stages, plus an assessment of physical activity performance expressed as a 4-point score; Pts are classified according to the highest stage recorded for either clinical condition or physical activity Categories Asymptomatic; mildly symptomatic; moderately symptomatic; severely symptomatic. See AIDS, HIV-1. WHO Staging System for HIV Infection Clinical Stage 1  1. Asymptomatic infection  .2. Persistent generalized lymphadenopathy  .3. Acute retroviral infection  Performance Stage 1: asymptomatic, normal activity Clinical Stage 2  .4. Unintentional weight loss < 10% body weight  .5. Minor mucocutaneous manifestations (e.g., dermatitis, prurigo, fungal nail infections, angular cheilitis)  .6. Herpes zoster within previous 5 years  .7. Recurrent upper respiratory tract infections Performance Stage 2: symptoms, but nearly fully ambulatory Clinical Stage 3  .8. Unintentional weight loss > 10% body weight  .9. Chronic diarrhea > 1 month  .10. Prolonged fever > 1 month (constant or intermittent)  .11. Oral candidiasis  .12. Oral hairy leukoplakia  .13. Pulmonary tuberculosis within the previous year  .14. Severe bacterial infections  .15. Vulvovaginal candidiasis Performance Stage 3: in bed > normal but < 50% of normal daytime during the previous month Clinical Stage 4  .16. HIV wasting syndrome .17. Pneumocystis carinii pneumonia  .18. Toxoplasmosis of the brain  .19. Crytosporidiosis with diarrhea > 1 month  .20. Isosporiasis with diarrhea > 1 month  .21. Cryptococcosis, extrapulmonary  .22. Cytomegalovirus disease of an organ other than liver, spleen or lymph node  .23. Herpes simplex virus infection, mucocutaneous  .24. Progressive multifocal leukoencephalopathy  .25. Any disseminated endemic mycois (e.g., histoplasmosis)  .26. Candidiasis of the esophagus, trachea, bronchi, or lung  .27. Atypical mycobacteriosis, disseminated  .28. Non-typhoid Salmonella septicemia  .29. Extrapulmonary tuberculosis  .30. Lymphoma  .31. Kaposi's sarcoma .32. HIV encephalopathy http://hivinsite.ucsf.edu/InSite?page=kb-01-01#S4X .