Weber-Christian syndrome

A rare idiopathic condition that primarily affects adult females; it is a diagnosis of exclusion.

Clinical findings
Crops of subcutaneous nodules on the thighs, abdomen, arms and breasts, accompanied by fever, local inflammation, rheumatic complaints (arthritis, arthralgia, myalgia), hepatosplenomegaly, abdominal pain and episcleritis.

Lab
Nonspecific; leukopenia, increased ESR, rheumatoid factor, cryoglobulinemia.

DiffDx
Erythema induratum, sarcoidosis, post-injection fat necrosis.
Management
Symptomatic relief with corticosteroids, chloroquine, phenylbutazone.

Weber-Christian syndrome

Relapsing nodular nonsuppurative panniculitis A rare idiopathic condition, which primarily affects adult ♀ Clinical Crops of subcutaneous nodules on the thighs, abdomen, arms, and breasts, accompanied by fever, local inflammation, rheumatic complaints–arthritis, arthralgia, myalgia, hepatosplenomegaly, abdominal pain, & episcleritis Lab Nonspecific; leukopenia, ↑ ESR, rheumatoid factor, cryoglobulinemia DiffDx Erythema induratum, sarcoidosis, postinjection fat necrosis Management Symptomatic relief with corticosteroids, chloroquine, phenylbutazone. See Panniculitis.

单词	weber-christian syndrome
释义	EncyclopediaSeeWeber-Christian disease Weber-Christian syndrome Weber-Christian syndrome A rare idiopathic condition that primarily affects adult females; it is a diagnosis of exclusion. Clinical findings Crops of subcutaneous nodules on the thighs, abdomen, arms and breasts, accompanied by fever, local inflammation, rheumatic complaints (arthritis, arthralgia, myalgia), hepatosplenomegaly, abdominal pain and episcleritis. Lab Nonspecific; leukopenia, increased ESR, rheumatoid factor, cryoglobulinemia. DiffDx Erythema induratum, sarcoidosis, post-injection fat necrosis. Management Symptomatic relief with corticosteroids, chloroquine, phenylbutazone. Weber-Christian syndrome Relapsing nodular nonsuppurative panniculitis A rare idiopathic condition, which primarily affects adult ♀ Clinical Crops of subcutaneous nodules on the thighs, abdomen, arms, and breasts, accompanied by fever, local inflammation, rheumatic complaints–arthritis, arthralgia, myalgia, hepatosplenomegaly, abdominal pain, & episcleritis Lab Nonspecific; leukopenia, ↑ ESR, rheumatoid factor, cryoglobulinemia DiffDx Erythema induratum, sarcoidosis, postinjection fat necrosis Management Symptomatic relief with corticosteroids, chloroquine, phenylbutazone. See Panniculitis.
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