synucleinopathy

synucleinopathy

(si-nook″lē-ĭn-op′ă-thē) Any degenerative disease of the central nervous system in which there is an excessive accumulation of alpha-synuclein (a brain protein) in the neurons. The synucleinopathies include Parkinson disease, dementia with Lewy bodies, and multiple system atrophy.