| Acronym | Definition |
|---|
| SPEN➣Stanford Project on the Evolution of Nonprofits (Stanford University; Stanford, CA) |
| SPEN➣Sports Penguin Entertainment Network (fictional broadcast network; Surf's Up) |
| SPEN➣Solid and Papillary Epithelial Neoplasm (radiology) |
| SPEN➣Scottish Peer Education Network (UK) |
| SPEN➣Statewide Police Emergency Network (for inter-agency communications during emergencies) |
| SPEN➣School Psychology E-Newsletter (Kentucky) |