Trasylol


Trasylol

 [tras´-lol] trademark for a preparation of aprotinin, an antihemorrhagic agent.

Trasylol

(trăs′ə-lŏl) A trademark for the drug aprotinin.

aprotinin

A bovine polypeptide and protease inhibitor with antifibrinolytic activity that derives from basic pancreatic trypsin inhibitor (BPTI), which was added to fibrinogen in “fibrin glue”, theoretically enhancing the persistence of the fibrin clot.
It was pulled from the international market in 2007, given the concern that aprotinin increased the risk of complications and death during surgery. In 2012 the European Medicines Agency concluded that the benefits outweighed the risks, and recommended the suspension be lifted.

Trasylol

A brand name for APROTININ.