alanine transaminase


alanine transaminase

 [al´ah-nēn trans-am´ĭ-nās] an enzyme that catalyzes the reversible transfer of an amino group from alanine to α-ketoglutarate to form pyruvate and glutamate. Normally present in many tissues and body fluids, especially in the liver, it is released into the serum as a result of tissue injury; the serum concentration is increased particularly when there is acute damage to hepatic cells, as in viral or toxic hepatitis, infectious mononucleosis, and obstructive jaundice. Called also alanine aminotransferase and glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase (ALT),

(al'ă-nēn a-mē'nō-tranz'fer-ās), An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); one d-alanine transaminase effects the same reaction, but using d-alanine and d-glutamate. Serum concentration is increased in viral hepatitis and myocardial infarction. Synonym(s): alanine transaminase, glutamic-pyruvic transaminase, serum glutamic:pyruvic transaminase

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās) An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās) An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase, alanine transaminase.