(al'-a-nē-glī-oks'i-lāt a-mē'nō-tranz'fĕr-ās), An enzyme that reversibly catalyzes the transfer of an amino group of l-alanine to glyoxylate, thus producing pyruvate and glycine. An inherited disorder that results in an alteration of alanine-glyoxylate aminotransferase activity is associated with primary hyperoxaluria type I.