alanine aminotransferase


alanine aminotransferase

 [al´ah-nēn ah-me″no-trans´fer-ās] ALT; alanine transaminase.

al·a·nine a·mi·no·trans·fer·ase (ALT),

(al'ă-nēn a-mē'nō-tranz'fer-ās), An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); one d-alanine transaminase effects the same reaction, but using d-alanine and d-glutamate. Serum concentration is increased in viral hepatitis and myocardial infarction. Synonym(s): alanine transaminase, glutamic-pyruvic transaminase, serum glutamic:pyruvic transaminase

alanine aminotransferase

Glutamine pyruvic transaminase, GPT Clinical chemistry An enzyme found primarily in the liver, with lesser amounts in the kidneys, heart and skeletal muscles; low levels of ALT are normal in the circulation; after liver damage, ALT is released into the bloodstream before more obvious clinical findings of liver damage–eg jaundice, occur; ↑ ALT is an early indicator of acute liver damage; ALT is measured as part of a panel of blood chemistry tests Ref ranges ♂ 10-32 U/L; ♀ 9-24 U/L; children 2 times > adults; AA is ↑ in viral hepatitis, drug-induced hepatitis, infectious mononucleosis, chronic hepatitis, intrahepatic cholestasis, cholecystitis, active cirrhosis, acute MI. See Aspartate amino transferase, Gamma-glutamyl transferase.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās) An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās) An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase, alanine transaminase.