sclerosing adenosis


scle·ros·ing ad·e·no·sis

a nodular, benign breast lesion occurring most frequently in relatively young women and consisting of hyperplastic distorted lobules of acinar tissue with increased collagenous stroma; the changes may be difficult to distinguish microscopically from carcinoma. Additionally, a benign nodular microscopic lesion of the prostate consisting of acinar tissue with increased stroma; the basal cell layer shows characteristic smooth muscle metaplasia. Synonym(s): adenofibrosis, fibrosing adenomatosis, fibrosing adenosis

scle·ros·ing ad·e·no·sis

(sklĕ-rō'sing ad'ĕ-nō'sis) 1. A nodular, benign breast lesion occurring most frequently in relatively young women and consisting of hyperplastic distorted lobules of acinar tissue with increased collagenous stroma; the changes may be difficult to distinguish microscopically from carcinoma. 2. A benign nodular microscopic lesion of the prostate consisting of acinar tissue with increased stroma; the basal cell layer shows characteristic smooth muscle metaplasia.
Synonym(s): adenofibrosis.