pyruvate dehydrogenase (lipoamide)

py·ru·vate de·hy·dro·gen·ase (lip·o·am·ide)

an oxidoreductase catalyzing conversion of pyruvate and (oxidized) lipoamide to CO₂ and S⁶-acetyldihydrolipoamide in two successive reactions: the first between pyruvate and thiamin pyrophosphate to yield CO₂ and α-hydroxyethylthiamin pyrophosphate (active pyruvate); the second between the last named and lipoamide to regain the thiamin pyrophosphate and yield S⁶-acetylhydrolipoamide. Compare: α-ketodecarboxylase.

单词	pyruvate dehydrogenase (lipoamide)
释义	EncyclopediaSeePyruvate Dehydrogenase pyruvate dehydrogenase (lipoamide) py·ru·vate de·hy·dro·gen·ase (lip·o·am·ide) an oxidoreductase catalyzing conversion of pyruvate and (oxidized) lipoamide to CO₂ and S⁶-acetyldihydrolipoamide in two successive reactions: the first between pyruvate and thiamin pyrophosphate to yield CO₂ and α-hydroxyethylthiamin pyrophosphate (active pyruvate); the second between the last named and lipoamide to regain the thiamin pyrophosphate and yield S⁶-acetylhydrolipoamide. Compare: α-ketodecarboxylase.
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