transporter associated with antigen processing

TAP1

A gene on chromosome 6p21.3 that encodes a member of the MDR/TAP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which plays a role in multidrug resistance. TAP1 pumps degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment.
Molecular pathology
TAP1 mutations have been tentatively linked to ankylosing spondylitis, type 1 diabetes and coeliac disease.

transporter associated with antigen processing

TAP

An intracellular protein that carries antigens to the endoplasmic reticulum of cells, where the antigens may be transformed for presentation.

单词	transporter associated with antigen processing
释义	DictionarySeetap transporter associated with antigen processing TAP1 A gene on chromosome 6p21.3 that encodes a member of the MDR/TAP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which plays a role in multidrug resistance. TAP1 pumps degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment. Molecular pathology TAP1 mutations have been tentatively linked to ankylosing spondylitis, type 1 diabetes and coeliac disease. transporter associated with antigen processing , TAP An intracellular protein that carries antigens to the endoplasmic reticulum of cells, where the antigens may be transformed for presentation. AcronymsSeeTAP2
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