plasminogen activator inhibitor-1


plas·min·o·gen ac·ti·va·tor in·hib·i·tor-1

(PAI-1) (plaz-min'ŏ-jen ak'ti-vā-tŏr in-hib'it-tŏr) Peptide adipokine produced by visceral adipose tissue; has a regulatory role in fibrinolysis and thrombus formation.

plasminogen activator inhibitor-1

A protein that degrades extracellular tissues. It has been linked to the invasive and metastatic spread of cancers.