| Acronym | Definition |
|---|
| SIG➣Special Interest Group |
| SIG➣Signal |
| SIG➣Signature |
| SIG➣Signor (Italian: Mister; used like Mr.) |
| SIG➣Système d'Information Géographique (French) |
| SIG➣Summer Institute for the Gifted |
| SIG➣Sistema de Información Geográfica (Spanish) |
| SIG➣Susquehanna International Group (Bala Cynwyd, Pennsylvania) |
| SIG➣School Improvement Grant (US Department of Education) |
| SIG➣Services Industriels de Genève (Switzerland) |
| SIG➣Software Installation Guide (instructions) |
| SIG➣Southern Indiana Gas and Electric Company |
| SIG➣Sigmoidoscopy |
| SIG➣Solomon Islands Government |
| SIG➣Signalman |
| SIG➣Service d'Information du Gouvernement (French: Department of Government Information) |
| SIG➣Support and Information Group |
| SIG➣Settings File |
| SIG➣Signature File |
| SIG➣Signaller |
| SIG➣Special Investigation Group (various locations) |
| SIG➣Sigmoidoscope |
| SIG➣Structural Informatics Group (Washington) |
| SIG➣Standardized Information Gathering (questionnaire) |
| SIG➣Spectrum Is Green (from the TV Series, Captain Scarlet) |
| SIG➣Strategy Implementation Group (various organizations) |
| SIG➣Secure Internet Gateway |
| SIG➣Social Issues Group (Malaysia) |
| SIG➣Surface Immunoglobulins |
| SIG➣SMDS Interest Group |
| SIG➣Strategic Initiatives Group (USMC) |
| SIG➣State Innovation Grant (US EPA) |
| SIG➣Senior Integration Group (US DoD) |
| SIG➣Senior Interdepartmental Group |
| SIG➣Stamford Industrial Group (Stamford, CT) |
| SIG➣Signature Investigations Group (Michigan) |
| SIG➣Small Inducible Gene (inflammatory response) |
| SIG➣Softgoal Interdependency Graph |
| SIG➣Stress in General (scale) |
| SIG➣Street Index Guide |
| SIG➣Single Instant Game |
| SIG➣System Integration Group |
| SIG➣Strategic Intelligence Group |
| SIG➣Shanghai International Group Corporation Limited |
| SIG➣Schweizerische Industrie Gesellschaft AG |
| SIG➣Selective Integral Ground |
| SIG➣Site Integration Group |
| SIG➣Self Inspection Guide |
| SIG➣Ship Improvement Guide |
| SIG➣PMW Poster Type File (Printmaster Premier 8.0 file extension) |
| SIG➣Specific Industry Group |
| SIG➣Staff Involvement Group (UK NHS) |
| SIG➣Strategic Integration Group |
| SIG➣Shanghai Industries Group, Ltd. (Shanghai, China) |
| SIG➣Service Instruction Guidance (University of Miami high school tutoring program) |
| SIG➣SSDS Interface Gateway |
| SIG➣Service Integration Gateway |