Uhthoff sign


Uht·hoff symp·tom

(ut'hof), a transient temperature-dependent numbness, weakness, or loss of vision. Conduction stops in any nerve if the temperature becomes too elevated. In a damaged nerve, for example, by demyelinization, this shutdown temperature is lowered, and may approach normal body temperature. Transient neurologic dysfunction may then appear with a hot shower, exercise, or fever. Synonym(s): Uhthoff syndrome

Uhthoff sign

(oot′hof″) [Wilhelm Uhthoff, Ger. ophthalmologist, 1853–1927] In patients with multiple sclerosis, the transient decrease in vision, double vision, or nystagmus when body temperature rises.