| 释义 |
restriction endonuclease
Thesaurus| Noun | 1. | restriction endonuclease - any of the enzymes that cut nucleic acid at specific restriction sites and produce restriction fragments; obtained from bacteria (where they cripple viral invaders); used in recombinant DNA technologyrestriction enzyme, restriction nucleaseendonuclease - a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes |
restriction endonuclease
restriction endonuclease[ri′strik·shən ¦en·dō′nü·klē‚ās] (cell and molecular biology) Any of the specific endonucleases that recognizes a short specific sequence within a deoxyribonucleic acid molecule and then catalyzes double-stranded cleavage of that molecule. Also known as endodeoxyribonuclease. restriction endonuclease
re·stric·tion en·do·nu·cle·aseone of many endonucleases isolated from bacteria that cleave or hydrolyze (cut) foreign double-stranded DNA chains at specific recognition sites defined by DNA sequences; these endonucleases have become standard laboratory devices for making specific cuts in DNA as a first step in deducing sequences and are sometimes referred to as a "chemical knife," usually named by a three- or four-letter abbreviation of the name of the organism from which isolated (for example, EcoB from Escherichia coli, strain B). Synonym(s): restriction enzymere·stric·tion en·do·nu·cle·ase (rĕ-strik'shŭn en'dō-nū'klē-ās) One of many endonucleases isolated from bacteria that hydrolyze (cut) double-stranded DNA chains at specific sequences, thus inactivating a foreign (viral or other) DNA and restricting its activity; standard laboratory devices for making specific cuts in DNA as a first step in deducing sequences.
Synonym(s): restriction enzyme. restriction enzyme or restriction endonuclease an endonuclease that recognizes a specific DNA base sequence (recognition sequence, recognition site, restriction sequence or restriction site) and cleaves both strands of DNA at or near that site. The enzyme cuts the DNA, generating restriction fragments with OVERHANGING ENDS or BLUNT ENDS. See also COHESIVE ENDS.AcronymsSeerheniumrestriction endonuclease
Synonyms for restriction endonucleasenoun any of the enzymes that cut nucleic acid at specific restriction sites and produce restriction fragmentsSynonyms- restriction enzyme
- restriction nuclease
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