| 释义 |
Side-chain theory
Side´-chain` the`o`ry
| 1.(Physiol. Chem.) A theory proposed by P. Ehrlich as a chemical explanation of immunity phenomena. In brief outline it is as follows: Animal cells and bacteria are complex aggregations of molecules, which are themselves complex. Complex molecules react with one another through certain of their side chains, but only when these side chains have a definite correspondence in structure (this accounts for the specific action of antitoxins). |
EncyclopediaSeePaul Ehrlichside-chain theory
side-chain the·o·ryEhrlich postulated that cells contained surface extensions or side chains (haptophores) that bind to the antigenic determinants of a toxin (toxophores); after a cell is stimulated, the haptophores are released into the circulation and become the antibodies.
See also: receptor. Synonym(s): Ehrlich postulateside-chain the·o·ry (sīd-chān thē'ŏr-ē) Ehrlich postulated that cells contain surface extensions or side chains (haptophores) that bind to the antigenic determinants of a toxin (toxophores); after a cell is stimulated, the haptophores are released into the circulation and become the antibodies.
See also: receptorEhrlich, Paul, German bacteriologist, immunologist, and Nobel laureate, 1854-1915. Ehrlichia - a genus of small, often pleomorphic, coccoid to ellipsoidal, nonmotile, gram-negative bacteria (order Rickettsiales) that are the etiologic agents of ehrlichiosis and are transmitted by ticks.Ehrlich anemia - anemia resulting from hypoplastic or aplastic bone marrow. Synonym(s): aplastic anemiaEhrlich diazo reagent - two solutions, one of sodium nitrite, the other of acidified sulfanilic acid, used in bringing about diazotization. Synonym(s): diazo reagentEhrlich inner body - a round oxyphil body found in the red blood cell in case of hemocytolysis due to a specific blood poison. Synonym(s): Heinz-Ehrlich bodyEhrlich phenomenon - the difference between the amount of diphtheria toxin that will exactly neutralize one unit of antitoxin.Ehrlich postulate - that cells contain surface extensions or side chains (haptophores) that bind to the antigenic determinants of a toxin (toxophores). Synonym(s): Synonym(s): Ehrlich theory; side-chain theoryEhrlich test - urobilinogen test using Ehrlich reagent.Ehrlich theory - Synonym(s): Ehrlich postulateEhrlich tumor - solid or ascitic transplantable tumor derived from breast carcinoma in mice.Ehrlich unitEhrlich-Türk line - seldom-used term for the thin vertical deposition of material on the posterior surface of the cornea seen in uveitis.Heinz-Ehrlich body - Synonym(s): Ehrlich inner body |