shunt nephritis

shunt nephritis

Immune complex glomerulonephritis seen in ± 4% of infants with infected ventriculoatrial, ventriculojugular or ventriculoperitoneal shunts Clinical Weight loss, lethargy, fever, lymphadenopathy, hepatosplenomegaly, HTN, arthralgia, nephrotic syndrome, often delayed recognition of infection Lab Anemia, microhematuria, proteinuria, azotemia; ↓ C3, rheumatoid factors, cryoglobulins; common bacteria–S epidermidis,.S albus Treatment Antibiotics, high-dose prednisone Prognosis12 resolve with therapy,14 have persistent urine abnormalities;14 die of the neurologic defects necessitating ventricular shunt