单词 | shunt nephritis |
释义 | shunt nephritisshunt nephritisImmune complex glomerulonephritis seen in ± 4% of infants with infected ventriculoatrial, ventriculojugular or ventriculoperitoneal shunts Clinical Weight loss, lethargy, fever, lymphadenopathy, hepatosplenomegaly, HTN, arthralgia, nephrotic syndrome, often delayed recognition of infection Lab Anemia, microhematuria, proteinuria, azotemia; ↓ C3, rheumatoid factors, cryoglobulins; common bacteria–S epidermidis,.S albus Treatment Antibiotics, high-dose prednisone Prognosis1⁄2 resolve with therapy,1⁄4 have persistent urine abnormalities;1⁄4 die of the neurologic defects necessitating ventricular shunt |
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