| 释义 |
vincristine
vin·cris·tine V0104800 (vĭn-krĭs′tēn′)n. An alkaloid, C46H56N4O10, originally obtained from the Madagascar periwinkle and used in its sulfate form to treat acute leukemia and a variety of other neoplasms.
[New Latin Vinca, periwinkle genus; see vinca + Latin crista, crest; see crest + -ine.]vincristine (vɪnˈkrɪstiːn) n (Pharmacology) a cytotoxic drug used in the treatment of leukaemia, derived as an alkaloid from the tropical shrub Madagascar periwinkle (Vinca rosea)[C20: from New Latin vinca + Latin crista crest + -ine2]vin•cris•tine (vɪnˈkrɪs tin)
n. an alkaloid, C46H56N4O10, derived from the periwinkle, Vinca rosea, used in treating certain cancers. [1960–65; < New Latin Vin(ca) a periwinkle genus + Latin crist(a) crest + -ine2] Thesaurus| Noun | 1. | vincristine - periwinkle plant derivative used as an antineoplastic drug (trade name Oncovin); used to treat cancer of the lymphatic systemOncovinperiwinkle plant derivative - an antineoplastic drug used to treat some forms of cancer |
Translationsvincristine
vincristine[vin′kri‚stēn] (pharmacology) C46H56O10N4 An alkaloid extracted from the periwinkle plant (Vinca rosea) and used, as the sulfate salt, as an antineoplastic drug. Also known as leurocristine. vincristine
vincristine [vin-kris´tēn] a vinca alkaloid used as an antineoplastic agent, primarily as a component of combination chemotherapy regimens for Hodgkin's disease, leukemia" >acute lymphoblastic leukemia, and non-Hodgkin's lymphomas, as well as in the treatment of other neoplastic disorders including tumor" >Wilms' tumor, neuroblastoma, AIDS-associated sarcoma" >Kaposi sarcoma, and rhabdomyosarcoma. Administered intravenously as the sulfate salt.vincristine (vĭn-krĭs′tēn′)n. An alkaloid, C46H56N4O10, originally obtained from the Madagascar periwinkle and used in its sulfate form to treat acute leukemia and a variety of other neoplasms.MOPP A 4-drug chemotherapy regimen for stage-III Hodgkin lymphoma.
Adverse effects
Sterility, nausea, vomiting, immunosuppression, increased infections, myelosuppression, myelodysplasia, ANLL.vincristine Oncovin® AIDS A dimeric vinca alkaloid used to treat KS, thrombocytopenia, leukemias, lymphomas, solid tumors and other CAs which, like vinblastine, interrupts the mitotic spindle, causing lysis of proliferating cells Adverse effects Reversible peripheral neuropathy, constipation. Cf Vinblastine. vincristine A vinca alkaloid anticancer drug used to treat LEUKAEMIA. The drug is on the WHO official list. A brand name is Oncovin.See VCR
See VCRvincristine
Related to vincristine: cyclophosphamide, methotrexate, prednisoneSynonyms for vincristinenoun periwinkle plant derivative used as an antineoplastic drug (trade name Oncovin)SynonymsRelated Words- periwinkle plant derivative
|