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DictionarySeeskinEncyclopediaSeepiebaldismpiebald skin
pie·bald·ism (pī-bawld'izm), [MIM*172800] Patchy absence of the pigment of scalp hair, giving a streaked appearance; patches of vitiligo may be present in other areas due to absence of melanocytes; often transmitted as an autosomal dominant trait caused by mutation in the KIT protooncogene on 4q and may be associated with neurologic defects [MIM*172850] or eye changes [MIM*172870]. Compare: Waardenburg syndrome. Synonym(s): cutaneous albinism, piebald skin, piebaldnesspiebald skin (1) Piebaldism, see there. (2) Vitiligo, see there.pie·bald·ness (pī'bawld-nĕs) Patchy absence of the pigment of scalp hair, giving a streaked appearance; patches of vitiligo may be present in other areas due to the absence of melanocytes. May be associated with neurologic defects or eye changes. Synonym(s): piebald skin, piebaldism. skinS09-865660 (skin) STRUCTURE OF THE SKIN AND SUBCUTANEOUS TISSUEThe organ that forms the outer surface of the body. It shields the body against infection, dehydration, and temperature changes; provides sensory information about the environment; manufactures vitamin D; and excretes salts and small amounts of urea. Skin consists of two major divisions: the epidermis and the dermis. Depending on its location and local function, skin varies in terms of its thickness, strength, presence of hair, nails, or glands, pigmentation, vascularity, nerve supply, and keratinization. Skin may be classified as thin and hairy or thick and hairless (glabrous). Thin hairy skin covers most of the body. Glabrous skin covers the surface of the palms of the hands, soles of the feet, and flexor surfaces of the digits. See: illustration; hair for illus; burn; dermatitis; dermis; eczema; epidermis; rash alligator skinSevere scaling of the skin with formation of thick plates resembling the hide of an alligator. See: ichthyosisartificial skinHuman skin equivalent.bronzed skinBrownish hyperpigmentation of the skin, seen in Addison's disease and hemochromatosis, some cases of diabetes mellitus, and cirrhosis.deciduous skinKeratolysis.elastic skinEhlers-Danlos syndrome.foreign bodies in the skinObjects that enter the skin accidentally or are inserted deliberately. The areas involved are cleaned carefully. Foreign material can be removed carefully piece by piece or by vigorous swabbing with gauze or a brush and a soapy solution. A sterile dressing should be used. For removal of a small foreign body, the area is cleaned first with mild soap and warm water. A clean needle can be sterilized by heating it to a dull or bright red in a flame; this can be done with a single match. Because both ends of the needle get hot, it is wise to hold the far end in a nonconductor such as a fold of paper or a cork. The needle is allowed to cool. A black deposit on its surface should be disregarded; it is sterile carbon and does not interfere with the procedure. The needle is introduced at right angles to the direction of the sliver, and the sliver is lifted out. Most people attempt to stick the needle in the direction of the foreign body and consequently thrust many times before they manage to lift the sliver out. When the sliver is removed, an antiseptic is applied and the wound covered with a sterile dressing. Tetanus antitoxin or a tetanus booster may be required, depending on the history of immunization. glabrous skinSkin that does not contain hair follicles, such as that over the palms and soles.glossy skinShiny appearance of the skin due to atrophy or injury to nerves.hidebound skinScleroderma.loose skinHypertrophy of the skin.parchment skinAtrophy of the skin with stretching.photoaged skinSkin changes caused by chronic sun exposure. This condition is prevented by avoiding suntanning and sunburning and has been treated with topical tretinoin and chemical peels. Synonym: photodamaged skinphotodamaged skinPhotoaged skin.piebald skinVitiligo.scarf skinThe cuticle, epidermis; the outer layer of the skin.sun-damaged skinPhotoaged skin.tissue-engineered skinHuman skin equivalent.true skinDermis.FinancialSeeSkin |