transcobalamin


transcobalamin

 [trans″ko-bal´ah-min] either of two plasma proteins, transcobalamin I and transcobalamin II, that bind and transport cobalamins, including vitamin B12 (see vitamin). Deficiency of transcobalamin II results in failure of immunoglobulin production, anemia" >megaloblastic anemia, granulocytopenia, thrombocytopenia, and intestinal villous atrophy, and is correctable by vitamin B12 therapy.