释义 |
DictionarySeereceptorT-cell receptor
T-cell receptor[′tē ‚sel ri‚sep·tər] (immunology) Protein on the surface of T lymphocytes that specifically recognizes molecules of the major histocompatibility complex, either alone or in association with foreign antigens. Abbreviated TCR. T-cell receptor
T-cell re·cep·tor (TCR) (sel rĕ-sep'tŏr) An adhesion molecule on the membrane of T lymphocytes, which serves as the receptor for antigen bound to antigen-presenting cells (APC) through MHC molecules. It is expressed in a complex with CD3. It is in proximity to the MHC-restricted receptor (CD4 or CD8). Synonym(s): T-lymphocyte antigen receptor. T-cell receptor Abbreviation: TCR One of two polypeptide chains (a or ß) on the surface of T lymphocytes that recognize and bind foreign antigens. TCRs are antigen specific; their activity depends on antigen processing by macrophages or other antigen-presenting cells and the presence of major histocompatibility complex proteins to which peptides from the antigen are bound. See: autoimmunity; immune response; T cellSee also: receptorSee TCR See TCR |