T-cell lymphoma


T-cell lymphoma

A malignant proliferation of T cells arising in the skin, diagnosed by detecting rearrangement of the T-cell receptor's β chain; TCLs are often 'driven' by EBV and other viral infections; 90% of all Pts with TCL have extracutaneous involvement when diagnosed. See Mycosis fungoides. T-cell lymphomas Small lymphocytic (well-differentiated lymphocyte-like) lymphoma–13% Convoluted cell lymphoma or poorly-differentiated lymphocytic lymphoma–52% Immunoblastic sarcoma or 'histiocytic' lymphoma–19% Mycosis fungoides/Sézary syndrome–11% Lymphoepithelial cell (Lennert's) lymphoma–5% Cutaneous T-cell lymphoma HTLV (I, II)–induced lymphoma

T-cell lymphoma

See MYCOSIS FUNGOIDES.