SAR1A


SAR1A

A gene on chromosome 10q22.1 that encodes a protein involved in transport from the endoplasmic reticulum to the Golgi apparatus. SAR1A is required to maintain SEC16A localisation at discrete locations on the ER membrane. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organised scaffold that defines endoplasmic reticulum exit sites (ERES).