单词 | uchl1 |
释义 | UCHL1UCHL1A gene on chromosome 4p14 that encodes a ubiquitin-protein hydrolase, involved both in processing of ubiquitin precursors and ubiquitinated proteins, which recognises and hydrolyses a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds free monoubiquitin and may prevent its degradation in lysosomes. |
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