释义 |
verapamil
ve·rap·a·mil V0059350 (və-răp′ə-mĭl′)n. A calcium channel blocker drug, C27H38N2O4, that acts as a coronary vasodilator and is used in its hydrochloride form to treat hypertension and certain cardiac arrhythmias. [vera(tryl), one of its constituents (from New Latin Vērātrum, hellebore genus; see veratrine) + -pamil, vasodilating drug suffix (perhaps p(ropyl) + am(ino) + (nitr)il(e)).]verapamil (vɪˈræpəˌmɪl) n (Pharmacology) med a calcium-channel blocker used in the treatment of angina pectoris, hypertension, and some types of irregular heart rhythmve•ra•pam•il (ˌvɪər əˈpæm əl, ˌvɛr-) n. a white, crystalline powder, C27H38N2O4, used as a calcium blocker in the treatment of angina and certain arrhythmias. [1965–70] ThesaurusNoun | 1. | verapamil - a drug (trade names Calan and Isoptin) used as an oral or parenteral calcium blocker in cases of hypertension or congestive heart failure or angina or migraineCalan, Isoptincalcium blocker, calcium-channel blocker - any of a class of drugs that block the flow of the electrolyte calcium (either in nerve cell conduction or smooth muscle contraction of the heart); has been used in the treatment of angina or arrhythmia or hypertension or migraine | TranslationsEncyclopediaSeeCalanverapamil
verapamil [vĕ-rap´ah-mil] a calcium channel blocking agent used as the hydrochloride salt as a coronary vasodilator in the treatment of angina pectoris and of hypertension and the treatment and prophylaxis of supraventricular tachyarrhythmias.verapamil (və-răp′ə-mĭl′)n. A calcium channel blocker drug, C27H38N2O4, that acts as a coronary vasodilator and is used in its hydrochloride form to treat hypertension and certain cardiac arrhythmias.verapamil Cardiology A CCB antiarrhythmic that slows transmission of impulses across the AV node and supresses the sinus node's intrinsic rhythm Indications Tachycardial supraventricular arrhythmias–eg, paroxysmal supraventricular tachycardia, A Fib with tachyarrhythmias, atrial flutter with rapid conduction, and is the parenteral emergency drug of choice Adverse effects Constipation, slowed AV conduction and sinus node automaticity, peripheral edema; it is a standard agent for managing HTN, especially in Pts with angina; it improves pain linked to obstructive cardiomyopathy, and prevents migraines Contraindications Severe left ventricular dysfunction, hypotension, sick sinus syndrome, 2º or 3º AV block, WPW, heart failure, or in Pts with accessory bypass tracts, WPW syndrome, peripheral edema; caution in renal failure. See Calcium channel blocker, Therapeutic drug monitoring. Cf Beta blocker. verapamil A calcium channel blocker drug used to correct irregularities in the heart beat. There is evidence that verapamil and other calcium channel blockers are anti-atherogenic and can prevent recurrent narrowing of arteries, such as the coronary arteries after these have been widened by CORONARY ANGIOPLASTY. The drug is on the WHO official list. Brand names are Cordilox, Securon, Univer and Vertab SR. Formulated with trandolapril it is marketed as Tarka.verapamil
Synonyms for verapamilnoun a drug (trade names Calan and Isoptin) used as an oral or parenteral calcium blocker in cases of hypertension or congestive heart failure or angina or migraineSynonymsRelated Words- calcium blocker
- calcium-channel blocker
|