ubiquitin-protease pathway

ubiquitin-protease pathway

pathway in which a small protein cofactor, ubiquitin, couples with protein substrate to catalyze proteolytic destruction by proteases; this pathway is highly selective and tightly regulated and is responsible for protein degradation seen in muscle-wasting diseases.

u·bi·qui·tin-pro·te·ase path·way

(yū-bik'kwi-tin-prō'tē-ās path'wā) Pathway in which a small protein cofactor, ubiquitin, couples with protein substrate to catalyze proteolytic destruction by proteases; this pathway is highly selective and tightly regulated and is responsible for protein degradation seen in muscle-wasting diseases.