| 释义 |
taxane
tax·ane T5068050 (tăk′sān′)n. Any of a class of anticancer drugs, such as paclitaxel, obtained from yew trees or synthesized, that inhibit the division of tumor cells by binding to and interfering with the action of microtubules.
[New Latin Tax(us), yew genus (from Latin taxus, yew) + -ane.]taxane
taxane (tăk′sān′)n. Any of a class of anticancer drugs, especially paclitaxel and docetaxel, that inhibit the division of tumor cells by binding to and interfering with the action of microtubules.tax·ane (taks'ān) Any of a class of antitumor agents derived directly or semisynthetically from Taxus brevifolius, the Pacific yew (e.g., paclitaxel and docetaxel). taxane (tăk′sān″) Any of a class of drugs derived from the bark of the yew tree, Taxus breviflora. Examples include paclitaxel and docetaxel. Taxanes are used to treat breast, ovarian, and other types of cancer. Side effects include bone marrow suppression, neuropathy, mucositis, and hypersensitivity reactions. taxane One of a group of diterpene substances derived from the Pacific yew tree Taxus brevifolia that have been found useful in cancer treatment. Taxanes have a unique action in permanently stabilizing the microtubule assembly in cells. This prevents chromosome movement and halts cell division. The taxane drugs, PACLITAXEL (Taxol) and docetaxal have been licensed for use and have been found capable of prolonging life as an adjuvant treatment in node-positive breast cancer. See also TAXOID DRUGS. |