phenocopy

phe·no·cop·y

P0240300 (fē′nə-kŏp′ē)n. pl. phe·no·cop·ies 1. An environmentally induced, nonhereditary trait in an organism that closely resembles a genetically determined trait, especially a mutation.2. An individual exhibiting such a trait.

[pheno(type) + copy.]

phenocopy

(ˈfiːnəʊˌkɒpɪ) n, pl -copies (Genetics) a noninheritable change in an organism that is caused by environmental influence during development but resembles the effects of a genetic mutation

phe•no•cop•y

(ˈfi nəˌkɒp i)

n., pl. -cop•ies. a trait or condition that resembles a known genetic defect but is externally caused and not inheritable. [< German Phänokopie (1935); see phenotype, copy]

Phenocopy

phenocopy

[¦fēn·ə¦käp·ē] (genetics) The nonhereditary alteration of a phenotype to a form imitating a mutant trait; caused by external conditions during development.

Phenocopy

a nonhereditary change in a phenotype, induced by specific environmental conditions and mimicking of some known hereditary change, or mutation, as exhibited in the phenotype. For example, nonhereditary teratism, or monstrosities, may be induced in the genetically normal embryos and larvae of some insects by various means, including high temperatures and vaporized ether; examples of such monstrosities, which may be observed in adult individuals, are a change in the number of legs or wings or the transformation of antennae into legs. These monstrosities are phenocopies of similar but hereditary changes that normally develop, in the absence of any external influence, in a number of mutant insect strains.

Phenocopies of various mutuations may be experimentally induced in other species of animals and plants as well. As a rule, the possible range of such phenocopies is not determined by the nature of the operative factor, but rather by the stage of development of the experimental organism. Presumably, some external factor that produces phenocopies in normal individuals interferes with the activity of the corresponding normal genes, resulting in the appearance of a mutant phenotype. The study of phenocopies is thus an important field of inquiry for phenogenetic research.

REFERENCES

Lobashev, M. E. Genetika. Leningrad, 1967.
Goldschmidt, R. B. Physiological Genetics. New York, 1938.

V. I. IVANOV

phenocopy

[fe´no-kop″e] 1. an environmentally induced phenotype mimicking one usually produced by a specific genotype.2. an individual exhibiting such a phenotype; the simulated trait in a phenocopy.

phe·no·cop·y

(fē'nō-kop'ē), An environmentally induced mimic of a disease that is characteristically produced by a specific gene. [G. phainō, to display, + copy]

phenocopy

(fē′nə-kŏp′ē)n. pl. phenocop·ies 1. An environmentally induced, nonhereditary trait in an organism that closely resembles a genetically determined trait, especially a mutation.2. An individual exhibiting such a trait.

phe·no·cop·y

(fē'nō-kop-ē) 1. A set of clinical and laboratory characteristics that would ordinarily warrant the diagnosis of a specific genetic abnormality, but are of environmental rather than genetic etiology. 2. A condition of environmental etiology that mimics one usually of genetic etiology. [G. phainō, to display, + copy]

phenocopy

A PHENOTYPE or disorder caused by non-genetic factors that mimics, and may be mistaken for, a genetic disorder.

phenocopy

a disorder or change that appears to be genetic in origin but actually is produced by environmental effects. An example is deafness in an infant that is caused by the GERMAN MEASLES virus rather than by an inherited condition. The distinction can be important in relation to the chances of an affected individual transmitting the condition to the next generation.

单词	phenocopy
释义	phenocopy phe·no·cop·y P0240300 (fē′nə-kŏp′ē)n. pl. phe·no·cop·ies 1. An environmentally induced, nonhereditary trait in an organism that closely resembles a genetically determined trait, especially a mutation.2. An individual exhibiting such a trait. [pheno(type) + copy.] phenocopy (ˈfiːnəʊˌkɒpɪ) n, pl -copies (Genetics) a noninheritable change in an organism that is caused by environmental influence during development but resembles the effects of a genetic mutation phe•no•cop•y (ˈfi nəˌkɒp i) n., pl. -cop•ies. a trait or condition that resembles a known genetic defect but is externally caused and not inheritable. [< German Phänokopie (1935); see phenotype, copy] Phenocopy phenocopy [¦fēn·ə¦käp·ē] (genetics) The nonhereditary alteration of a phenotype to a form imitating a mutant trait; caused by external conditions during development. Phenocopy a nonhereditary change in a phenotype, induced by specific environmental conditions and mimicking of some known hereditary change, or mutation, as exhibited in the phenotype. For example, nonhereditary teratism, or monstrosities, may be induced in the genetically normal embryos and larvae of some insects by various means, including high temperatures and vaporized ether; examples of such monstrosities, which may be observed in adult individuals, are a change in the number of legs or wings or the transformation of antennae into legs. These monstrosities are phenocopies of similar but hereditary changes that normally develop, in the absence of any external influence, in a number of mutant insect strains. Phenocopies of various mutuations may be experimentally induced in other species of animals and plants as well. As a rule, the possible range of such phenocopies is not determined by the nature of the operative factor, but rather by the stage of development of the experimental organism. Presumably, some external factor that produces phenocopies in normal individuals interferes with the activity of the corresponding normal genes, resulting in the appearance of a mutant phenotype. The study of phenocopies is thus an important field of inquiry for phenogenetic research. REFERENCES Lobashev, M. E. Genetika. Leningrad, 1967. Goldschmidt, R. B. Physiological Genetics. New York, 1938. V. I. IVANOV phenocopy phenocopy [fe´no-kop″e] 1. an environmentally induced phenotype mimicking one usually produced by a specific genotype.2. an individual exhibiting such a phenotype; the simulated trait in a phenocopy. phe·no·cop·y (fē'nō-kop'ē), An environmentally induced mimic of a disease that is characteristically produced by a specific gene. [G. phainō, to display, + copy] phenocopy (fē′nə-kŏp′ē)n. pl. phenocop·ies 1. An environmentally induced, nonhereditary trait in an organism that closely resembles a genetically determined trait, especially a mutation.2. An individual exhibiting such a trait. phe·no·cop·y (fē'nō-kop-ē) 1. A set of clinical and laboratory characteristics that would ordinarily warrant the diagnosis of a specific genetic abnormality, but are of environmental rather than genetic etiology. 2. A condition of environmental etiology that mimics one usually of genetic etiology. [G. phainō, to display, + copy] phenocopy A PHENOTYPE or disorder caused by non-genetic factors that mimics, and may be mistaken for, a genetic disorder. phenocopy a disorder or change that appears to be genetic in origin but actually is produced by environmental effects. An example is deafness in an infant that is caused by the GERMAN MEASLES virus rather than by an inherited condition. The distinction can be important in relation to the chances of an affected individual transmitting the condition to the next generation.
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