| Acronym | Definition |
|---|
| TISC➣Tertiary Institutions Service Centre |
| TISC➣The Internet Security Conference |
| TISC➣Tool Interface Standard Committee |
| TISC➣Toronto Island Sailing Club (Ontario, Canada) |
| TISC➣Technology Integration Steering Committee |
| TISC➣Theater Information Systems Command |
| TISC➣TRADOC Integration Staff Officer |
| TISC➣Treasury Information Service Center |
| TISC➣The Iceland Submarine Cable |
| TISC➣Tucker Inn and Strange Crew (Michigan Technological University; Houghton, MI) |
| TISC➣Thorney Island Sailing Club (UK) |