proto-oncogene

pro·to-on·co·gene

P0617750 (prō′tō-ŏn′kə-jēn′, -ŏng′kə-)n. A normal gene that has the potential to become an oncogene.

Thesaurus

Noun

proto-oncogene - a normal gene that has the potential to become an oncogenecistron, gene, factor - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"

proto-oncogene

[pro″to-ong´ko-jēn] a normal gene that with slight alteration by mutation or other mechanism becomes an oncogene.

proto-oncogene

(prō′tō-ŏn′kə-jēn′, -ŏng′kə-)n. A normal gene that has the potential to become an oncogene.

proto-oncogene

Molecular medicine A normal gene with latent transforming potential, homologous to a retroviral oncogene Examples
c-erb, c-fos, c-jun, c-myb, c-myc, c-mos, c-raf, c-ras; POs act in normal growth, differentiation, and induction and/or maintenance of CA. See Abl, cyclin D1, RET/PTC.

proto-oncogene

Any gene capable of becoming a cancer-producing gene (an oncogene). Proto-oncogenes have important functions in the normal cell, but, by mutation or by the acquisition of genetic control elements from oncoviruses they can lose their normal regulatory functions and lead to uncontrolled multiplication.

proto-oncogene

a gene that normally functions to initiate or maintain cell division. However, it can be converted into an ONCOGENE by, for example, MUTATION.

proto-oncogene

pro·to-on·co·gene

proto-oncogene

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proto-oncogene

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Words related to proto-oncogene

noun a normal gene that has the potential to become an oncogene

Related Words