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单词 sheehan's syndrome
释义 DictionarySeesyndrome

Sheehan's syndrome


Sheehan's syndrome

[′shē·ənz ‚sin‚drōm] (medicine) Pituitary necrosis caused by insufficient blood supply to the gland due to copious blood loss or intravascular clotting and hemorrhage associated with premature separation of the placenta during childbirth. Also known as postpartum pituitary necrosis.

Sheehan's syndrome


necrosis

 [nĕ-kro´sis, ne-kro´sis] (Gr.) the morphological changes indicative of cell death caused by enzymatic degradation.aseptic necrosis necrosis without infection or inflammation.acute tubular necrosis acute renal failure with mild to severe damage or necrosis of tubule cells, usually secondary to either nephrotoxicity, ischemia after major surgery, trauma (see crush syndrome), severe hypovolemia, sepsis, or burns. See also lower nephron nephrosis.Balser's fatty necrosis gangrenous pancreatitis with omental bursitis and disseminated patches of necrosis of fatty tissues.bridging necrosis septa of confluent necrosis bridging adjacent central veins of hepatic lobules and portal triads characteristic of subacute hepatic necrosis.caseous necrosis caseation (def. 2).central necrosis necrosis affecting the central portion of an affected bone, cell, or lobule of the liver.cheesy necrosis caseation (def. 2).coagulation necrosis death of cells, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time.colliquative necrosis liquefactive necrosis.fat necrosis necrosis in which fat is broken down into fatty acids and glycerol, usually occurring in subcutaneous tissue as a result of trauma.liquefactive necrosis necrosis in which the necrotic material becomes softened and liquefied.massive hepatic necrosis massive, usually fatal, necrosis of the liver, a rare complication of viral hepatitis (fulminant hepatitis) that may also result from exposure to hepatotoxins or from drug hypersensitivity.moist necrosis necrosis in which the dead tissue is wet and soft.postpartum pituitary necrosis see postpartum pituitary necrosis.selective myocardial cell necrosis myofibrillar degeneration.subcutaneous fat necrosis of newborn a benign, self-limited disease affecting term newborns and young infants, characterized by circumscribed, indurated, nodular areas of fat necrosis. It is thought to be related to trauma on bony prominences during delivery, hypothermia, asphyxia, or maternal diabetes; it usually resolves spontaneously by 2 to 4 weeks with no scarring. Called also adiponecrosis neonatorum or subcutanea.Zenker's necrosis degeneration" >hyaline degeneration and necrosis of striated muscle; called also Zenker's degeneration.

postpartum

 [pōst-pahr´tum] occurring after childbirth, with reference to the mother.postpartum pituitary necrosis necrosis of the pituitary during the postpartum period, resulting from an infarct; it is often associated with shock and excessive uterine bleeding during delivery, and leads to variable patterns of hypopituitarism. Called also Sheehan's syndrome.

Sheehan's syndrome

The effects of destruction of the front part of the PITUITARY GLAND by loss of its blood supply (infarction) following severe bleeding from the womb after delivery of a baby (postpartum haemorrhage). There is failure of milk production, loss of body hair, absence of menstruation, lethargy and other effects of underaction of the endocrine glands. (Professor Harold Leeming Sheehan, 1900–86, English physician).
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