| 释义 |
DictionarySeeboxTATA box
TATA box[′tä‚tä ‚bäks or ¦tē¦ā¦tē′ā ‚bäks] (genetics) In eukaryotes, a short sequence of base pairs that is rich in adenine (A) and thymidine (T) residues and located about 25-30 nucleotides upstream of the transcriptional initiation site. TATA box
TATA boxa highly conserved bacterial DNA sequence found about 25 bp upstream from the transcription start site of genes, usually flanked by GC-rich sequences; binding site of transcription factors but not RNA polymerase.TATA box or Hogness box a short CONSENSUS SEQUENCE generally to be found in the PROMOTOR in EUKARYOTES. The sequence consists of seven or eight NUCLEOTIDES: 5′-TATA(A/T)A(A/T)-3′. It is located about 25 to 30 base pairs UPSTREAM of the start of the TRANSCRIPTION site and serves as a binding site for RNA POLYMERASE. It is similar to the PRIBNOW BOX in PROKARYOTES.FinancialSeeBox |