单词 | shc4 |
释义 | SHC4SHC4A gene on chromosome 15q21.1-q21.2 that encodes a signalling adapter protein which activates Ras-dependent and Ras-independent migratory pathways in melanomas. SHC4 contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1, and it interacts with MUSK and GRB2. It is highly expressed at the transition from radial growth phase to vertical growth phase and metastatic melanomas, when tumour cells acquire migratory competence and invasive potential. |
随便看 |
英语词典包含2567994条英英释义在线翻译词条,基本涵盖了全部常用单词的英英翻译及用法,是英语学习的有利工具。