释义 |
DictionarySeecyclooxygenaseprostaglandin endoperoxide synthase
prostaglandin endoperoxide synthase [pros″tah-glan´din en″do-per-ok´sīd sin´thās] an enzyme of the oxidoreductase class that has both cyclooxygenase and peroxidase activities, which together catalyze part of the synthesis of prostaglandins and thromboxanes from arachidonic acid.pros·ta·glan·din en·do·per·ox·ide syn·thasea protein complex that catalyzes two steps in prostaglandin biosynthesis; the cyclooxygenase activity (which is inhibited by aspirin and indomethacin) converts arachidonate and 2O2 to prostaglandin G2; the hydroperoxidase activity uses glutathione to convert prostaglandin G2 to prostaglandin H2. Synonym(s): cyclooxygenase |