Antabuse
An·ta·buse
A0325050 (ăn′tə-byo͞os′)Antabuse
(ˈæntəˌbjuːs)| Noun | 1. |  Antabuse - a drug (trade name Antabuse) used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingested |
| 单词 | antabuse | |||
| 释义 | AntabuseAn·ta·buseA0325050 (ăn′tə-byo͞os′)Antabuse(ˈæntəˌbjuːs)
AntabuseAntabuse(ăn`təbyo͞os), trade name for the drug tetraethylthiuram disulfide, used in the treatment of alcoholismalcoholism,disease characterized by impaired control over the consumption of alcoholic beverages. Alcoholism is a serious problem worldwide; in the United States the wide availability of alcoholic beverages makes alcohol the most accessible drug, and alcoholism is the most ..... Click the link for more information. . Also called sulfiram, Antabuse is nontoxic, but it alters the metabolism of alcohol in the body, making it impossible for one who is taking the drug to drink without experiencing severe discomfort. When alcohol is present the drug increases the concentration of acetaldehyde in the body, causing symptoms resembling those of a bad hangover: the individual feels hot, the face becomes flushed, the neck and head throb, and nausea, vomiting, and headache may follow. Small quantities of alcohol, such as from food sauces and cough medicines, and even inhaled traces from shaving lotions and varnishes, may induce the same symptoms. The drug Temposil, or citrated calcium carbamide, has the same function as Antabuse, but is weaker and safer. The therapeutic use of Antabuse was discovered in the 1930s when workers exposed to tetraethylthiuram disulfide, a chemical used in the rubber industry, became ill after drinking alcoholic beverages. AntabuseAntabuse[an´tah-būs]Antabuse(ăn′tə-byo͞os′)Antabuse®Disulfuram, see there.AntabuseDisulfiram. A drug sometimes used in the management of alcoholism, which causes severe nausea and vomiting, sweating, breathlessness, headache and chest pain if any alcohol is taken after it has been given. Disulfiram inhibits the enzyme aldehyde dehydrogenase that breaks down acetaldehyde, a toxic metabolite of alcohol, so that this accumulates. The method is a form of aversion therapy and is not without danger of collapse and death from the toxic effects.Antabuse
Synonyms for Antabuse
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