tyramine hypertension

tyramine hypertension

A complication of monoamine oxidase inhibitors (MAOIs), which are used to treat depression and panic disorders. MAOIs inhibit the metabolism of tyramines and catecholamines; ingestion of tyramine-rich food and/or beverages (e.g., Chianti wine, cheddar cheese, naturally fermented beer, chicken liver, or drugs such as ephedrine and amphetamines) evokes an acute hypertensive crisis due to the release of tissue catecholamines, which may be accompanied by sweating, tachycardia or arrhythmia.

tyramine hypertension

Cheese disease Nutrition A complication of MAOI therapy, used to treat depression and panic disorders; MAOIs inhibit the metabolism of tyramines and catecholamines; ingestion of tyramine-rich food and/or beverages–eg, Chianti wine, cheddar cheese, beer, chicken liver or drugs–eg, ephedrine, amphetamines, evokes an acute hypertensive crisis due to the release of tissue catecholamines, which may be accompanied by sweating, tachycardia, or arrhythmias