释义 |
SGK1 SGK1 A gene on chromosome 6q23 that encodes serum/glucocorticoid-inducible kinase 1, a serine/threonine protein kinase that activates certain K+, Na=, and Cl- channels in response to cell stress, and which appears to be involved in cell survival, neuronal excitability and renal sodium excretion. It is highly expressed in hypertension and diabetic nephropathy. |