| 释义 |
proinsulin
pro·in·su·lin P0587950 (prō-ĭn′sə-lĭn)n. A single-chain polypeptide that is the precursor of insulin, converted into insulin by enzymatic action.proinsulin (prəʊˈɪnsjʊlɪn) n (Physiology) the naturally synthesized precursor to insulin
EncyclopediaSeeINSproinsulin
proinsulin [pro-in´soo͡-lin] a precursor of insulin, having low biologic activity.pro·in·su·lin (prō-in'sŭ-lin), A single-chain precursor of insulin.proinsulin (prō-ĭn′sə-lĭn)n. A single-chain polypeptide that is the precursor of insulin, converted into insulin by enzymatic action.INS A gene on chromosome 11p15.5 that encodes preproinsulin, which is cleaved post-translationally into the B- and A-chain peptides (which are covalently linked via two disulfide bonds to form insulin) and C-peptide. Insulin reduces blood glucose and increases cell permeability to monosaccharides, amino acids and fatty acids, and accelerates glycolysis, the pentose phosphate cycle and glycogen synthesis in the liver.pro·in·su·lin (prō-in'sŭ-lin) A single-chain precursor of insulin. |