sacral defect with anterior meningocele


sacral defect with anterior meningocele

An autosomal dominant form (OMIM:600145) of caudal dysgenesis that is present at birth and becomes symptomatic later in life, usually due to obstructive labour in females, chronic constipation or meningitis.
Molecular pathology
Defects of VANGL1 are a cause of sacral defect with anterior meningocele.