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DictionarySeesyndromeSezary syndrome
Sezary syndrome[sə′zar·ē ‚sin‚drōm] (medicine) Exfoliative erythroderma with a cutaneous infiltrate of atypical mononuclear cells; similar cells are also present in the peripheral blood. Sezary syndrome
Sézary syndrome [sa´zah-re] a form of cutaneous T-cell lymphoma manifested by generalized exfoliative erythroderma, intense pruritus, peripheral lymphadenopathy, and abnormal hyperchromatic mononuclear cells in the skin, lymph nodes, and peripheral blood (Sézary cells).Sé·za·ry syn·drome (sā-zah-rē'), exfoliative dermatitis with intense pruritus, resulting from cutaneous infiltration by atypical mononuclear cells (T lymphocytes with markedly convoluted or cerebriform nuclei) also found in the peripheral blood, and associated with alopecia, edema, and nail and pigmentary changes; a variant of mycosis fungoides. Synonym(s): Sézary erythroderma
Sé·za·ry syn·drome (sā-zah-rē'), exfoliative dermatitis with intense pruritus, resulting from cutaneous infiltration by atypical mononuclear cells (T lymphocytes with markedly convoluted or cerebriform nuclei) also found in the peripheral blood, and associated with alopecia, edema, and nail and pigmentary changes; a variant of mycosis fungoides. Synonym(s): Sézary erythrodermaSezary syndrome Mycosis fungoides, see there. Sé·za·ry syn·drome (sā-zah-rē' sindrōm) Exfoliative dermatitis with intense pruritus, resulting from cutaneous infiltration by atypical mononuclear cells also found in the peripheral blood, and associated with alopecia, edema, and nail and pigmentary changes; a variant of mycosis fungoides. Sezary syndrome A rare condition featuring a malignant spread of excessive numbers of abnormal T LYMPHOCYTES in the blood, with enlarged lymph nodes and deposits in the skin, liver and spleen. There are red, scaly patches on the skin extending to form a widespread, itchy and flaking rash, hair loss and distortion of the nails. The condition is thought to be caused by a retrovirus, HTLV-I. Treatment is with anticancer drugs and RADIOTHERAPY. (Albert Sezary, 1880–1956, French physician).Sézary syndromeA leukemic phase of CTCL that develops in some patients, characterized by the appearance of malignant T cells in the peripheral blood and sometimes in the lymph nodes. The syndrome is named for Alfred Sézary (1880–1956), a French dermatologist.Mentioned in: Cutaneous T-Cell LymphomaBouvrain, Y., French physician. Sézary-Bouvrain syndrome - Synonym(s): Sézary syndrome
Sézary, Albert, French dermatologist, 1880-1956. Sézary-Bouvrain syndrome - Synonym(s): Sézary syndromeSézary cell - an atypical T lymphocyte seen in the peripheral blood in Sézary syndrome.Sézary erythroderma - Synonym(s): Sézary syndrome; Sézary-Bovrain syndromeSézary syndrome - a variant of mycosis fungoides. Synonym(s): Sézary-Bouvrain syndrome; Sézary erythrodermaAcronymsSeesafe sex |