Sabin-Feldman dye test

Sa·bin-Feld·man dye test

(sā'bĭn feld'măn), a method for the detection of antitoxoplasma antibody in serum, based on the finding that Toxoplasma gondii cells (from peritoneal exudate in mice) are fairly well stained with alkaline methylene blue, whereas organisms in a serum that contains specific antibody have no affinity for the dye; furthermore, normal toxoplasma cells become rounded, and the nucleus and cytoplasm deeply stained, when treated with methylene blue; conversely, when dye is mixed with organisms and antibody, the cells retain their crescent shape and only the shrunken nuclear endosome is stained.

Feldman,

Harry Alfred, U.S. epidemiologist, 1914–. Sabin-Feldman dye test - see under SabinSabin-Feldman syndrome - see under Sabin

Sabin,

Albert Bruce, U.S. epidemiologist, 1906-1993. Sabin-Feldman dye test - a method for the detection of antitoxoplasma antibody in serum.Sabin-Feldman syndrome - chorioretinitis and cerebral calcifications.Sabin vaccine - an orally administered vaccine containing live, attenuated strains of poliovirus.

单词	sabin-feldman dye test
释义	DictionarySeeAlbert Bruce Sabin Sabin-Feldman dye test Sa·bin-Feld·man dye test (sā'bĭn feld'măn), a method for the detection of antitoxoplasma antibody in serum, based on the finding that Toxoplasma gondii cells (from peritoneal exudate in mice) are fairly well stained with alkaline methylene blue, whereas organisms in a serum that contains specific antibody have no affinity for the dye; furthermore, normal toxoplasma cells become rounded, and the nucleus and cytoplasm deeply stained, when treated with methylene blue; conversely, when dye is mixed with organisms and antibody, the cells retain their crescent shape and only the shrunken nuclear endosome is stained. Feldman, Harry Alfred, U.S. epidemiologist, 1914–. Sabin-Feldman dye test - see under SabinSabin-Feldman syndrome - see under Sabin Sabin, Albert Bruce, U.S. epidemiologist, 1906-1993. Sabin-Feldman dye test - a method for the detection of antitoxoplasma antibody in serum.Sabin-Feldman syndrome - chorioretinitis and cerebral calcifications.Sabin vaccine - an orally administered vaccine containing live, attenuated strains of poliovirus.
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