periosteal osteosarcoma

per·i·os·te·al os·te·o·sar·co·ma

chondroblastic osteosarcoma occurring on the surface of bones without involvement of the marrow; usually presents in adolescents and young adults as a lucent defect with bone spicules extending into soft tissues. Histologically, the tumor is intermediate to high grade, and the cartilage is lobulated.

periosteal osteosarcoma

An uncommon (less than 2%) osteosarcoma (OS) with the same demographic as conventional OS. It is related to periosteal chondrosarcoma, and usually arises in diaphysis of the proximal tibia or distal femur.
Imaging
Small radiolucencies on bone surface with bone spicules perpendicular to shaft and penetrating soft tissues; no medullary involvement.
DiffDx
Parosteal chondrosarcoma—lobules of malignant cartilage with calcification and surface endochondral ossification, no malignant osteoid.
Genetics
Usually diploid.
Prognosis
Intermediate between high-grade and parosteal (juxtacortical) OSs or chondrosarcoma; high local recurrence; 15% metastasise.

单词	periosteal osteosarcoma
释义	DictionarySeeosteosarcoma periosteal osteosarcoma per·i·os·te·al os·te·o·sar·co·ma chondroblastic osteosarcoma occurring on the surface of bones without involvement of the marrow; usually presents in adolescents and young adults as a lucent defect with bone spicules extending into soft tissues. Histologically, the tumor is intermediate to high grade, and the cartilage is lobulated. periosteal osteosarcoma An uncommon (less than 2%) osteosarcoma (OS) with the same demographic as conventional OS. It is related to periosteal chondrosarcoma, and usually arises in diaphysis of the proximal tibia or distal femur. Imaging Small radiolucencies on bone surface with bone spicules perpendicular to shaft and penetrating soft tissues; no medullary involvement. DiffDx Parosteal chondrosarcoma—lobules of malignant cartilage with calcification and surface endochondral ossification, no malignant osteoid. Genetics Usually diploid. Prognosis Intermediate between high-grade and parosteal (juxtacortical) OSs or chondrosarcoma; high local recurrence; 15% metastasise.
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