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单词 stat1
释义

STAT1


STAT1

A gene on chromosome 2q32.2 that encodes a member of the STAT family of transcription factors, which are phosphorylated by receptor-associated kinases in response to cytokines and growth factors. The STAT1 protein product is activated by IFN-alpha, IFN-gamma, EGF, PDGF and IL6; it mediates the expression of various genes, which is important for cell viability in response to different cell stimuli and pathogens.

STAT1


AcronymDefinition
STAT1Signal Transducer and Activator of Transcription 1 (also seen as STAT-1)
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