| 释义 |
sevelamer Translationssevelamer
sevelamer [sĕ-vel´ah-mer] a binder" >phosphate binder used as the hydrochloride salt to reduce serum phosphorus concentrations in hyperphosphatemia associated with end-stage renal disease; administered orally.sevelamer A phosphate chelator used to reduce phosphorus in patients with end-stage renal disease and in chronic renal failure patients not requiring dialysis. It also reduces uric acid levels, and may be of use in patients with hyperuricaemia, uric acid nephrolithiasis and gout. Adverse effects Blood pressure lability (hypo- or hypertension), nausea, vomiting, dyspepsia, diarrhoea, constipation.sevelamer Renagel® Nephrology A chelator used to ↓ phosphorus in Pts with ESRD and in chronic renal failure Pts not requiring dialysis. See Chelation, End-stage renal disease. |